The DNA of a Psychopath

Science is still trying to discover the biological nature of psychopathy, the DNA makes up one part, but could the blood group Rhesus Negative blood group also play an important Factor??

The GENETIC connection:

An extra chromosome: which is two pieces stuck together on the q arm. – is called isodicentric and has no family connections with the chromosomal abnormality as it forms by chance.  No links to environmental or lifestyle factors. Therefore, there is nothing that parents did before, or during pregnancy to cause the mutation.

On GENE 15;

  •                 Interstitial = high functioning
  •                 Isodicentric = low functioning

Savant skills are a result of GABRB3 –  on long arm of gene 15. Therefore: innate – born this way.

  •                 If the DNA is interstitial, it indicates exceptional intelligence. Cerebral = SAVANT
  •                 If DNA is isodicentric, it indicates more in more severe expression. Sexual = Sexual deviance and pervasive sexual appetite?

Psychopath skills of mental manipulation is learnt, through society, cultures, and familial traditions.

A savant raised in a supportive environment where he was given opportunities may remain balanced and in control, if his pre-frontal cortex is not too damaged, he will be able to connect to his emotions, due to modelling of loving environment; however if his amygdala has been affected by trauma, a different outcome is expected due to the change of neurological pathway and the neurological peptides, (which create patterns in the brain that drive behaviours and addictions). 

Amygdala – MID BRAIN

The amygdala’s are two almond-shaped masses of neurons on either side of the thalamus at the lower end of the hippocampus.  When it is stimulated electrically, animals respond with aggression.  And if the amygdala is removed, animals get very tame and no longer respond to things that would have caused rage before.  But there is more to it than just anger:  When removed, animals also become indifferent to stimuli that would have otherwise have caused fear and even sexual responses! The amygdala  is often referred to as the mammalian ‘monkey’ brain, responsive to fear/trauma and indifference/love. Could this be what we are observing through social trends, growing autism diagnosis, Asperger’s, ADHD and other pervasive disorders!

The ventral tegmental area of the brain stem (just below the thalamus) consists of dopamine pathways that seem to be responsible for pleasure.  People with damage here tend to have difficulty getting pleasure in life, and often turn to alcohol, drugs, sweets, and gambling. Depression maybe

The basal ganglia (including the caudate nucleus, the putamen, the globus pallidus, and the substantia nigra) lie over and to the sides of the limbic system, and are tightly connected with the cortex above them.

  • Responsible for repetitive behaviours, reward experiences, and focusing attention. 

The FORE BRAIN – NEO cortex

The prefrontal cortex, which is the part of the frontal lobe which lies in front of the motor area, is also closely linked to the limbic system.  Involved in thinking about the future, making plans, and taking action, it’s also involved in the same dopamine pathways as the ventral tegmental area, and plays a part in pleasure and addiction.

Is there a cure: YES… its called neuroplasticity!

Neuroplasticity: The brain’s ability to reorganize itself by forming new neural connections throughout life. Neuroplasticity allows the neurons (nerve cells) in the brain to compensate for injury and disease and to adjust their activities in response to new situations or to changes in their environment.


Neuroplasticity isn’t exclusive to psychopathy, its universal, meaning it can re-wire anything…. The cure to all dysfunctional, deviant behaviours, CAN be cured, by re-wiring the brain. The most important factor in all neurological injuries, is the WILL of the PERSON… Do they WANT to change their behaviour? That’s the underlying factor for any measure of success!

Responsibility and Accountability over one’s OWN behaviour, attitude and EGO plays a major role. There is NO EXCUSE for deviant behaviour, only the persons own WILL and refusal acknowledge they have a problem is one of the biggest barriers to good mental health.

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